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A new dawn for cataracts

On Thursday, November 6, scientists from ViewPoint Therapeutics published an article titled “Pharmacological chaperone for α-crystallin partially restores transparency in cataract models” in Science Magazine. The lead author: ViewPoint’s founder and CSO, Leah Makley. The summary below is from the linked perspective in the same issue. Cataract, a clouding of the eye lens, is the major cause of blindness in […]

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Symic Biomedical Advances First Product Candidate, SB-030, Into Clinical Development

Symic Biomedical, a clinical-stage biotherapeutics platform company developing compounds that target the extracellular matrix (ECM), today announced the treatment of the first patient in its Phase 1/2 clinical Study in Humans to Investigate the Efficacy and Safety of Luminal SB-030 Delivery in Peripheral Artery Disease (SHIELD Trial). The study will evaluate the safety and efficacy of SB-030 (previously SBCV-030), a […]

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Amarantus seeks US FDA orphan drug status for eltoprazine

Amarantus Bioscience Holdings, Inc., a biotechnology company, has submitted a request to the US FDA for orphan drug designation (ODD) for eltoprazine in the treatment of levodopa-induced dyskinesia (PD-LID). “A successful application to the US FDA for ODD for eltoprazine in PD LID would complete the transition of our therapeutics portfolio into the orphan drug arena, thereby squarely positioning Amarantus […]

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Military researchers to conduct trial of Amarantus’s “engineered skin substitute”

Cooperative research and development efforts with the military, universities and the biotech industry can potentially lead to advancements in the treatment of severe wounds.  Biotech companies with recent developments, partnerships and advancements in focus are Amarantus Bioscience Holdings, Inc. (OTCQX: AMBS), Array BioPharma, Inc. (NASDAQ: ARRY), Avanex Life Sciences Corp. (OTCQX: AVXLD), Juno Therapeutics, Inc. (NASDAQ: JUNO), and Progenix Pharmaceuticals, […]

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Now You Can Buy Shampoo and Cleanser That Promote the Growth of “Good” Bacteria

If you’ve heard about probiotic cosmetic spray, it’s probably from a New York Times Magazine story published last year. In that article, journalist Julia Scott profiled the startup AOBiome and recounted her experience using the company’s signature product, a spray “contain[ing] billions of cultivated Nitrosomonas eutropha, an ammonia-oxidizing bacteria (AOB) that is most commonly found in dirt and untreated water.” […]

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AOBiome Announces Start of First Clinical Trial with Ammonia Oxidizing Bacteria-Based Therapeutic for Treatment of Acne

AOBiome today announced it has begun a Phase 2 clinical trial with a therapeutic product candidate based on its proprietary ammonia oxidizing bacteria (AOB) for the treatment of mild to moderate acne vulgaris. The trial with the product candidate, B244, is being conducted under an IND application to the FDA and is the first to test the potential of live […]

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Robots And Microbes: Zymergen Raises $44 Million From Big VCs

The two biology experts–one a biophysicist, one a biochemist–were studying microbes, the single-cell organisms found all over the planet, to see how they could be used as building blocks to produce new renewable materials. Sick of how slow the typical process can be, testing 10 ideas or so a month, they looked to robots to speed up their  painstaking lab […]

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Golden Helix integrates MedGenome’s OncoMD into its VarSeq software

Golden Helix Inc., a leading bioinformatics solutions provider, has now announced the integration of MedGenome’s OncoMD into their VarSeq software. The integration will provide VarSeq users with the option to access over 2 million annotated cancer variants. OncoMD is a comprehensive knowledge base of cancer-specific genetic alterations captured from peer-reviewed scientific publications by a team of biomedical curators. After filtering […]

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AOBiome Announces Three Senior Management Appointments

AOBiome today announced three appointments to its senior management team to advance the company’s business to develop first-in-class skin health products based on Ammonia Oxidizing Bacteria (AOB). Joining the company are: Ramesh Ratan, Chief Financial Officer (CFO); Todd Krueger, Chief Business Officer (CBO); and Jim Hoffman, Head of Marketing. “Ramesh, Todd, and Jim each bring decades of experience in leadership […]

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Ethan Perlstein featured in CNET story on “science labs in the cloud”

Science is hard. Repeating other labs’ findings is even harder. That’s particularly true in the life sciences, where biologists and researchers manually run sophisticated experiments fraught with variables such as water purity, humidity or subtle differences in equipment. “Biologists do almost everything by hand, and there’s a lot of variation in experiments from lab to lab,” said Ethan Perlstein, founder […]

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