Research Associate- In Vivo Pharmacology

http://gpcr.co.kr/career/

Research Associate- In Vivo Pharmacology GPCR THERAPEUTICS, USA
The Company

Join an exciting venture-backed startup in San Carlos with a novel approach for targeting GPCRs. Located in San Carlos, CA and in S. Korea, GPCR Therapeutics, Inc. http://gpcr.co.kr, is a venture backed startup company developing pharmaceuticals against G Protein-Coupled Receptors (GPCRs) based on cutting-edge technology. The company has discovered specific GPCR heteromers which, when formed, result in enhanced cell signaling. Drugs that target disease-specific heteromers in cancer are under development.

Research Associate, Pharmacology

GPCR Therapeutics, USA is now building a foundational R&D team, and we have an opening for an experienced and motivated Research Associate to support multiple in vivo pharmacology studies. This is an opportunity to create a significant impact on our portfolio by helping us in lead selection and advancement.

Main Roles & Responsibilities

The Research Associate will be part of Therapeutic R&D division of GPCR Therapeutics, USA.  As a member of a cross-disciplinary team, this employee will support advancement of our portfolio by characterizing small molecule and biologics in rodent models by measuring response to therapy and in vivo mechanism of action studies. The position will report directly to Scientist II and requires the ability to work closely within multiple teams.

Key Responsibilities

Work in close collaboration with other members of the team in the characterization of small molecules and therapeutic antibodies
Perform in vivo pharmacology experiments in mice to investigate PK/PD and efficacy of drug candidates.
Prepare drug solutions, conduct dosing (IV, IP, SC, PO), measure tumor volumes, monitor health and collect blood and tissue samples.
Collect tissue samples as needed for investigational purpose such as IHC
Perform ex-vivo Flow on tumor to determine infiltrating leukocyte changes
Interpret, record, and present biological data.
Maintain compliance with all company policies and procedures.
Personal Qualities:

Demonstrated strong work ethic, curiosity to learn and contribute in a fast-paced collaborative environment
Excellent communication and organizational skills
Self-starter who can take initiative
Excellent analytical and problem-solving skills
Can streamline workflow and multitask
Ability to work in a collegial manner, a team player
Highly tolerant and respectful of all members of a small startup company
Ideal Educational Requirements and Experience:

S. or M.S. in Biology with 2+ years relevant experience in academia or industry.
Hands-on experience with mouse disease models, preferably in oncology, is essential.
Extensive experience with drug delivery procedures (IV, IP, SC, PO), and blood and tissue collection.
Proficiency in Microsoft Excel, Word and PowerPoint.
Strong sense of priorities and ability to troubleshoot experiments.
Excellent communication and presentation skills, capable of conveying technical information in a clear manner.
Detail-oriented, with excellent organizational and record-keeping skills
Preferred qualifications:

Bioluminescent/fluorescence imaging using an IVIS Spectrum In Vivo Imaging System.
Experience in sterile cell culture techniques, and in vitro/ex vivo immune cell-based assays.
Experience with FLOW cytometry is a plus.
Compensation

We offer a competitive salary, commensurate of a young startup in Silicon Valley, plus generous stock option allocations and benefits.

Corporate Culture at GPCR Therapeutics, USA

We are a small company that fosters a respectful, friendly, informal, and non-hierarchical work environment. We embrace rigorous and meticulous science with a belief in continuous growth and learning. We strive for excellence in performance and quality of work, and at the same time, we believe in maintaining a healthy work/life balance.

If you are interested in this opportunity, I would be happy to set up a time to speak with you. Please send a copy of your resume to:

pina.cardarelli@gpcr.co.kr