Please join us for a Lunch Seminar featuring former Amgen Golden Ticket Winner, SiteOne Therapeutics Sponsored by Lunch served RSVP John Mulcahy PhD, co-founder and Vice President of Research at SiteOne Therapeutics, has a background in synthetic organic chemistry, drug discovery and neuroscience. As a graduate student, he developed technology to prepare synthetic analogues of natural toxins that are potent, small molecule inhibitors of mammalian voltage-gated sodium ion channels. SiteOne has leveraged this technology, as well as structural insights into the binding pose of the natural toxins, to design novel drug candidates with exquisite selectivity for the human nociceptive sodium channel, NaV1.7, as non-opioid therapeutics for the treatment of pain. John received a PhD in Chemistry from Stanford University and AB in Chemistry, Physics and Classics from Harvard.

Founders At Work Speaker Series RSVP Zachary Hill, PhD, is co-founder and President of Soteria Biotherapeutics, a protein engineering company focused on developing next-generation T-cell therapies for the treatment of cancer. Prior to founding Soteria, Zach was a postdoctoral fellow in the laboratory of Professor Jim Wells at UCSF, where he helped to co-invent the technological basis for Soteria’s founding. While at UCSF, Zach was a Helen Hay Whitney Fellow, as well as the recipient of a NIH K99/R00 Transition Award from the NCI. Zach received his PhD in organic chemistry from the University of Washington, where he worked under the direction of Professor Dustin Maly on the development of bivalent inhibitors of protein kinases. Zach’s scientific interests sit at the interface of proteins and small molecules, with an emphasis on developing novel therapeutics. James A. Wells, PhD is Professor in the Department of Pharmaceutical Chemistry at UCSF. The Wells’ group pioneered the engineering of proteins, antibodies, and small molecules that target catalytic, allosteric, and protein-protein interaction sites; and technologies including protein phage display, alanine-scanning, engineered proteases for improved hydrolysis, bioconjugations, N-terminomics, disulfide “tethering” (a novel site-directed fragment based approach for drug discovery), and more recently an industrialized recombinant antibody […]